Field of Expertise

Bioprocess development

Expertise

The activity of the Fermentation Pilot Plant (PPF) is focused on those industries that require facilities suitable for the development of processes and/or the production on a pilot scale. Companies of the following sectors could be included:  Pharma and veterinary: antigens, antibodies, toxins for diagnosis, pharmacologically active proteins, plasmid DNA, etc.  Fine chemistry: biosynthesis of optically active molecules, enzymes for biotransformations, etc.  Food and Agriculture industry: starters, fungicide, bactericide, food additives, etc.  Cosmetics: active ingredients. Main services offered by the PPF are: R+D+I of biotecnological processes  Design, development and optimization of bioprocesses.  Identification and characterization of microorganisms.  Culture medium design.  Growth and production kinetics.  Analytical methods implementation.  Culture strategies study.  Scale-up development.  Downstream development. Production processes at pilot scale  Production of large quantities of biotechnological products and/or cell biomass.  Production under Standard Operating Procedures (SOP). Training and advising  Training of specialized personnel for biotechnological companies.  Advising and process analysis. E. coli recombinant protein production platform  Proprietary strain and vector antibiotic free expression system.  Fast gene to protein workflow.  High cell density fermentation platform.