This invention has the potential, as a consumer product or therapy, to prolong human lifespan by reducing the body’s levels of microbial methionine production.

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Background: In fewer than 10 years, the number of people aged 65 and older worldwide will outnumber the number of children under 5 for the first time in history, with the over-65 population expected to double by 2050. With these areas of growth has come a demand among aging populations for products and services that will enable them to live happier, healthier, and even longer lives. In fact, almost 80% of the U.S. Baby Boomer generation is taking steps to feel and remain young. Thus, a growing market demand has been created within the global anti-aging market. Anti-aging products include procedures and medications intended to delay, stop, or slow aging processes. This technology embodies a proven method of extending lifespan by a process of genetically modifying certain species of bacteria that naturally occur in the human gut. This invention produces microbes that lower the levels of the amino acid methionine in the body, and studies have shown that reduced levels of dietary methionine lead to increased lifespan. Consequently, this invention has the potential, as a consumer product or therapy, to prolong human lifespan by reducing the body’s levels of microbial methionine production.   About the Market: The global cosmetics and toiletries industry is a $333.0 billion industry and the antiaging segment is the fastest growing area of this industry. The global market for anti-aging products is poised to grow at a CAGR of 7.5% from $140.3 billion in 2015 to $216.52 billion in 2021, and some projections claim the market could reach one trillion dollars by 2025. Increasing aging populations worldwide, a major driving factor for this market, have resulted in growing demand for anti-aging products and services. North America has traditionally dominated this market due to elevating awareness of signs of aging as well as increased obesity in the region. Furthermore, despite recent economic downturn, consumers have continued to spend money on anti-aging products, indicating the value consumers place on retaining youth and prolonging lifespan.  

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