Excessive expression of melanin can lead to skin diseases such as freckles, brown spots, chloasmas, & even melanoma. We have a new agent to prevent & treat these skin problems

About

This invention provides the whitening effect of acetylcholinesterase inhibitor and its action mechanism. Acetylcholinesterase inhibitors have excellent inhibitory effect on UV-induced melanin production. By inhibiting the activity of acetylcholinesterase, acetylcholine can enhance the inhibition of melanin production-related genes (such as tyrosinase, tyrosinase-related protein, microphthaliam-related transcription factor) expression, thus having skin whitening effect. Meanwhile, those drugs showed no significant toxic effect melanocytes and keratinocytes, so they can be used as whitening agents on the skin and effectively prevent the deposition of melanin such as freckles and brown spots.

Key Benefits

A new kind of safe whitening compound acetylcholinesterase inhibitor with excellent whitening effect is found by using biological activity and new mechanism as the screening index. The technical scheme adopted by the invention to solve the technical problem is: a kind of whitening agent, the whitening agent includes the effect of inhibiting the activity of ache. The invention also provides a whitening agent for inhibiting the generation of melanin. The invention also provides a whitening agent for inhibiting the expression of tyrosinase. The invention also provides a whitening agent for inhibiting the expression of transcription factors related to microphthalmia. The invention also provides a whitening cosmetics, including the whitening agent. The invention also provides a whitening medicine product, including the whitening agent. The whitening agent of the invention and its application have the following beneficial effects: the whitening agent with acetylcholinesterase inhibitor as the main component of the invention can achieve excellent skin whitening effect by inhibiting the generation of melanin, which can greatly benefit the cosmetics and whitening medicine products applied to skin whitening.

Applications

Cosmetics and medicines

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