Biomanufacturing of long-chain wax esters (mainly C32~C36) as biolubricants from waste cooking oils via metabolically engineered yeast (Y. lipolytica) and bacteria (E. coli).


Long-chain wax esters (C32-C36) are produced at high titer and yield from waste cooking oils by metabolically engineered yeast and bacteria, which are generated by Prof. Dongming Xie's lab in Department of Chemical Engineering at University of Massachusetts Lowell (UMass Lowell, or UML). The produced wax esters can be used to replace those high-quality wax esters from the Sperm Whales and Jojob Plant. In addition to the application as biolubricants, the produced wax esters can also be used for cosmetics and other purposes.

Key Benefits

(1) High titer and yield from engineered yeast or bacteria;
(2) Using waste cooking oils as the economical raw materials;
(3) Microbial fermentation for large scale production;
(4) Long-chain wax esters (C32-C36) with high qualities to replace those from Sperm Whales and Jojob plants.


Biolubricants, cosmetics, food ingredients, pharmaceuticals.

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