A biocompatible liposome transfection agent
The PEGylated positively-charged liposome has been used to deliver a DNA payload and to release it over time in a biologically-relevant medium. This lipoplex exhibits significantly lower toxicity than commercially available agents such as jetPRIME, while demonstrating efficient internalization into the nucleus and DNA delivery.
Biocompatible: improved cell viability relative to commercially available lipofection agents. Efficient: validated efficient delivery of DNA cargo into cells and nuclei.