Register for free to
view the full innovation profile.
The sensor can help distinguish D-glucose from other biologically significant monosaccharides and has the potential to be used in monitoring urine glucose level of diabetics.
About
INVENTION Novelty of this sensor rests in the use of the specially designed tetraphenylethene-based diboronic acid (TPEDB) as a fluorescent probe for selective detection of D-glucose. In the past decade, through elaborate molecular structure design, two boronic acid groups are attached to a fluorophore at the “correct” position with an effort to ensure the formation of 1:1 complex between probe and D-glucose and to enhance the affinity between probe and D-glucose. Utilization of AIE mechanism of restriction of intramolecular rotation, an “analyst-conformation dependent probe” has replaced previous “affinity dependent probe”, and has greatly improved the selectivity. MARKET OPPORTUNITY The sensor can help distinguish D-glucose from other biologically significant monosaccharides and has the potential to be used in monitoring urine glucose level of diabetics. Key Benefits Easy to synthesize High selectivity towards detection of glucose