It is dose controllable (even at very low doses), it is patient-driven and has non-passive operation and a no press-and-breathe coordination.


Summary   Researchers at the University of New Mexico have developed a dry powder inhaler based upon the intense aero-mechanical forces generated during flutter.  The flutter element is configured to vibrate in response to airflow through the chamber and aerosolize the dose of powdered medicament.  During flutter, the intense vibrational energy concentrated in the film dislodges and deaggregates the drug from the film to allow for efficient and reproducible respiratory drug delivery. This device allows for the dry powder drug to be delivered (as a pure drug with no excipient) from a patient-driven, simple, scalable device. Advantages include; Delivery of pure drug with no excipient, efficient and uniform drug delivery, non-Ozone depleting , allows delivery of dry powder formulations, requires minimal parts and is small in size , has better performance, at lower device resistance than current inhalers , tunable (to drug powder, lung function, lung target) , rapid development timelines, easy embodiment as single or multi-dose device, high dose capable (i.e. mg’s), low variability as dispersion mechanism not solely based on fluid detachment, multiple drug compatible and ability to retrofit existing multi-dose devices with dispersion “Engine.

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