Novel Microbial Control Approach via Molecular roadblocks for RpoN binding sites

About

An engineered peptide represses expression of various bacterial genes controlled by the global regulator RpoN, thus shutting down many metabolic pathways that bacteria need for growth, infection, and virulence. The method can be used to inhibit bacterial motility, growth, quorum sensing, attachment, virulence, and biofilm formation. Patents: U.S. 9,392,790; 9,879,051 SUNY-ESF-1816

Key Benefits

(1) Bio-control capabilities. (2) Low risk of resistance. (3) Broad spectrum.

Applications

Antimicrobial infection control.

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