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Novel fluorescent biocompatible probe to detect oxidative damage in live cells and tissues in as little as 5 minutes
About
The technology comprises a novel fluorescent biocompatible probe that can detect oxidative damage as biomolecule carbonylation in live cells and tissues in as little as 5 minutes. This probe outperforms various commercially available toxicity and reactive oxygen species assays, demonstrating superior sensitivity and signal-to-noise ratios.
Key Benefits
Rapid: assay time as low as 5 minutes Sensitivity: Magnitudes more sensitive than available oxidative damage probes Simplicity: 1- or 2-step protocol for microtiter plate or microscopy detection
Applications
Research reagent: biomolecule carbonylation Research reagent: general oxidative stress levels Screening tool: rapid cell toxicity screening Diagnostic: detection of oxidative stress in live tissues, including cancer tissues