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Ref: 06523
Oxygen Isotope Analyses
Carbonic Anhydrase-Catalyzed Isotope Equilibrium for Oxygen Isotope Analyses
This patent pending method reduces oxygen isotope equilibrium reaction time from 24h to <1h
About
Background Oxygen isotope studies of aqueous samples are typically determined through the isotopic equilibration of CO2 gas and H2O. This equilibration process typically takes 24 hours in a closed undisturbed reaction vessel, limiting laboratory throughput. Technology Overview The technique developed at McMaster utilizes carbonic anhydrase (CA) to rapidly catalyze the oxygen isotope exchange reaction, bringing the reaction time from 24 hours to less than one hour. This technique is compatible with commercially available CO2-H2O equilibration devices, and can be easily and immediately adopted by any laboratories that measure the oxygen isotope compositions of aqueous samples. Stage of Development: Experimentally verified. Data is available upon request. 19-020
Key Benefits
• Reduce equilibrium reaction time from 24h to <1h. • Increase laboratory throughput capability. • Compatible with existing commercially available equipment.
Applications
Oxygen Isotope analyses in fields such as: • Environmental sciences: Geology, Hydrology • Carbonate isotope analyses • Biology • Medical