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The invention applies an external stimulus to the stationary phase of liquid chromatography to alter the polarity of the solvent during a separation process.
About
Variable Solvent Polarity Chromatography Tech ID: UA19-282 Invention: In this invention, an external stimulus is applied to the stationary phase of liquid chromatography to alter the polarity of the solvent during a separation process. This capability enables improved separations with more efficient use of mobile phase. The chromatographic separation method can be designed with flexible equipment and machine learning. Background: Chromatography is a well-established process and is widely used for laboratory chemical separation; however, it is problematic for large scale use. Enhancements in separation efficiency will be useful to many areas of research and industry including: - Pharmaceutical active ingredients - Fine chemicals - Environmental separations - Life sciences - Separations of complex mixtures
Key Benefits
- Improved performance in chromatography separations - Increased resolution - More efficient use of mobile phase - Less waste - Can enable commercial scale separations
Applications
- Compound purification and/or chemical separations