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SpheriSomes® in this application are novel, multi-lamellar microparticles which consist entirely of naturally occurring fatty acids and a natural GRAS approved food preservative
About
SpheriSome® microspheres consist entirely of the naturally antimicrobial fatty acid, sebacic acid which is cross-linked with an approved food preservative poly-epsilon-lysine using our patented technology. The base component is poly-epsilon-lysine which is well-documented in the scientific literature as an antimicrobial peptide discovered in Japan in the 1980s. Poly-epsilon-lysine is currently manufactured on a multi-tonne scale by a fermentation process. The antibacterial and anti-fungal properties of our unique cross-linked microparticles are well proven and the underlying technology patented by the company in 2012 and is acknowledged in many peer reviewed publications in the scientific literature. A patent covering the SpheriSome® technology specifically for cosmetic, personal care and home care applications was granted in 2019. SpheriSomes® can be further collaboratively engineered or further developed for specific uses, for example, coatings, film, gels, sprays, creams, solutions and suspensions to meet customer specifications. Other amino acid combinations, incorporation of active substances into the multi-laminar layers to further customise to expand the initial formulations to meet the required performance criteria. SpheriSomes® have also been engineered to immobilise other specific ingredients such as antioxidants (vitamin C) and UV to NIR (700nm-1400nm) blockers such as zinc oxide and titanium oxide.
Key Benefits
SpheriSomes® provide a foundation upon which a multiplicity of materials and or products can be developed which exploit its inherent antimicrobial properties and microencapsulation of active ingredients. Healthcare and pharmaceuticals, cosmetics, personal care and homecare are few of the applications open to development.
Applications
SpheriSomes® have been developed by SpheriTech, an independent research, development, and manufacturing company focused on developing novel and innovative polymeric materials which offer wide-ranging application solutions to clients to the benefit of multiple target markets such as life science research, biotechnology, and healthcare industries. Added benefit is the transfer of knowledge in its application from one market to another. Some examples are alcohol-free a hand sanitiser based upon SpheriSomes® called SpheriLyse®. The 2µm biodegradable microparticles in the SpheriLyse® formulation are small enough to be trapped in crevices in the skin and are retained on the skin for long periods. A new formulation will be launched in due course containing linoleic acid immobilised on SpheriSomes®. It is important to note that linoleic acid has been proven to block the active site of COVID-19. A toothpaste is in development using the SpheriSomes® with encapsulated dicalcium phosphate for enamel repair. Similarly, zinc oxide has been trapped within SpheriSomes® for an anti-dandruff treatment. Zinc oxide is commonly used in sunscreens to block UV light and light in the region of interest, 700-1400nm. The ultimate benefit is the ability to work with clients to understand, design and developed specific tailored solutions.